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Amgen NASDAQ: AMGN pharmaceutical company just announced outstanding performance results for Pivotal Postmenopausal Osteoporosis Trial for denosumab.
Trial reached primary endpoint of Diminishing new vertebral fractures and secondary endpoints of decreasing time to first non-vertebral and hip fractures; adverse events similar to placebo. The immediate past president of the National Osteoporosis Foundation Stated Cory Joseph Jersey , ” I am particularly excited about these findings because they indicate that denosumab may offer an important new option for patients.”
Denosumab is the premier fully human monoclonal antibody in late stage clinical development that specifically targets RANK Ligand, an essential regulator of osteoclasts the cells that break down bone). Denosumab is being investigated for its potential to inhibit every stage of osteoclast activity by a targeted mechanism. Denosumab is being studied in a range of bone loss illnesses such as, rheumatoid arthritis, postmenopausal osteoporosis Joe Young Jersey , and cancer treatment-induced bone loss in breast cancer and prostate cancer patients| in prostate cancer and breast cancer patients as well as for its potential to delay bone metastases and inhibit and treat bone destruction across many stages of cancer.
Osteoporosis is often referred to as the “silent epidemic”, osteoporosis is a world wide problem illness that is increasing in significance as the world population both ages and increases. WHO, The World Health Organization has just identified osteoporosis as a priority health issue in addition to other major non-communicable diseases. We are dependent on the pharmaceutical industry to help combat this terrible disease.
Amgen states that the financial burden of osteoporosis is referred to as the “silent epidemi’ to that of other major chronic diseases; for example, in the U.S. the costs associated with osteoporosis-related fractures are equivalent to those of cardiovascular disease and asthma (i)(ii)(iii). It has been reported that osteoporosis results in more hospital bed-days than stroke Lance Stephenson Jersey , myocardial infarction or breast cancer (iv).
Pharmacist-clinical have been developing prescriptions drugs to help patient who experience serious side effects. These products are developed simultaneously the medications that aid in the treatment of the primary illness. The fact that data is available to help predict the potential side effects and interactions drugs have with each other is outstanding.
These medicines are prescribed to prevent and treat osteoporosis. A few prescriptions increase bone thickness or slow the rate of bone loss. Even small amounts of new bone growth may reduce the danger of broken bones. It is essential that you take calcium and vitamin D, exercise and eat well when you take osteoporosis prescriptions.
With so many medications being produced and approved it is overwhelming to fathom how doctors, pharmacists, pharmacy techs Mark Jackson Jersey , can keep pace with the data.
At last is the perfect information conduit. They provide audios with over five hundred commonly prescribed medications. Medical professionals and the public can also subscribe to the monthly updates at no charge. Audio learning? This is a welcome resource. The audio includes interactions, side effects, indications, and mechanism of action. When else will these busy people have an opportunity to keep abreast the newest medications?
It is easy to find a doctor who has not heard of an approved drug that may have fewer adverse interactions with other drugs or treat an illness more effectively. When was the last time a doctor prescribed a less effective drug than one that Did the doctor prescribe the most current drug? No one knows.